ALCOHOLISM & SUBSTANCE ABUSE RESEARCH
$433,905 awarded to research since 1985
According to the National Alliance on Mental Illness (NAMI), about half of people with a mental illness abuse alcohol or other substances. The Foundation of Hope funds research that seeks to better understand the causes of substance abuse, explore its relationships to other illnesses, and find novel treatments that could, for example, help turn the tide of America’s opioid crisis.
Active Research
Reversing the pharmacological effects of cocaine by allopregnanolone | Robinson
Reversing the pharmacological effects of cocaine by allopregnanolone Need/Problem: There is a critical need for pharmacological therapeutics to treat stimulant addiction, for which there are no approved drugs. Grant Summary: This project will test [...]
Oxytocin Effects on Cocaine-induced Maternal Neglect | Grewen | $40,000
Oxytocin Effects on Cocaine-induced Maternal Neglect Award: $40,000 Need/Problem: At least 1% to 3% of women in the U.S. use cocaine during pregnancy. Prenatal cocaine abuse is linked to problems with mother-infant bonding and [...]
Defining, Mining, and Reversing Neurocircuit Adaptions in Addiction | Stuber | $100,000
Defining, Mining, and Reversing Neurocircuit Adaptions in Addiction Award: $100,000 Addiction alters the signaling and function of many neurons in the brain. Because drug or alcohol abuse alter our neurocircuitry—the pathways of our brains—reversing [...]
Alcohol intoxication mediated through medial septal circuitry | Knapp | $39,210
Alcohol intoxication mediated through medial septal circuitry Award: $39,210 In this research, researchers will use a novel mouse line to test the involvement of a specific neural circuit in brain in controlling alcohol intoxication. [...]
Testing oxytocin treatment of opioid withdrawal | Pedersen | $40,808
Testing oxytocin treatment of opioid withdrawal Award: $40,808 Opioid use disorders have emerged as a public health crisis over the past 20 years; opioid overdose is now the leading cause of death for United [...]