In 2020, we’re thrilled to report the below research discoveries and scientific publications:
1. Individual differences in the brain structure of 6 year olds are present by age 1. This indicates that a large portion of what makes each human brain unique, and likely the risk for psychiatric disease associated with these individual differences, is already present in the first year of life.
Gilmore JH, Langworthy BW, Girault JB, Fine J, Jha SC, Kim SH, Cornea E, Styner M. Individual variation of human cortical structure is established in the first years of life. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 2020; 5:971-980. PMID: 32741702.
2. Genes of risk for schizophrenia, especially those expressed in the placenta during pregnancy, interact with environmental risk factors before and during birth to alter early childhood brain structure and cognitive development.
Ursini G, Punzi G, Langworthy B, Chen Q, Xai K, Cornea E, GoldmanBD, Styner M, Knickmeyer RC, Gilmore JH*, Weinberger DR* (co-senior author). Placental genomic risk for schizophrenia predicts early neurodevelopmental outcomes. Proc Natl Acad Sci U S A 2021; 118: e2019789118.