Fetal Brain Development Assessed In-Utero with Ultrasound: Implications for Subsequent Neurodevelopmental Abnormalities & Risk of Neuropsychiatric Illness
$29,600 seeded → $26.7 MILLION LEVERAGED GROWTH
Growth Sponsor: National Institute of Mental Health (NIMH)
Research Summary: The pilot grant from the Foundation of Hope allowed Dr. Gilmore to begin his pioneering work developing neuroimaging methods to study very early childhood brain development. Dr. Gilmore ultimately established the UNC Early Brain Development study, a longitudinal study of brain development in over 1000 children, including at children at risk for schizophrenia and other psychiatric disorders, from birth through age 10 years.
Results and Next Steps: This innovative study has received multiple NIH grants, has generated many publications, and has defined normal brain development in early childhood for the first time. This work is ongoing and seeks to identify early markers of risk for psychiatric illness, so that interventions to reduce the ultimate risk of psychiatric illness can targeted to very early childhood, when brain systems are being established.