SCHIZOPHRENIA RESEARCH
$1,553,129 awarded to research since 1985
Schizophrenia is a serious mental illness that inhibits a person’s ability to think clearly, recognize reality, interact with others, and manage emotions. Symptoms can include hallucinations, delusions, hearing voices, flat emotional expression, and disorganized or obsessive thinking. While the disease isn’t common, it still affects 3.2 million Americans, and can have devastating consequences for a sufferer’s ability to keep a job or maintain interpersonal relationships. Despite its relative lack of prevalence, its severity and high mortality rate makes schizophrenia the Foundation’s most highly funded area of study.
Active Research
Developing and Evaluating a Computable Phenotype for Treatment-Resistant Schizophrenia | Zeng | $41,302
Developing and Evaluating a Computable Phenotype for Treatment-Resistant Schizophrenia 2021 Award: $41,302 Treatment-Resistant Schizophrenia affects about 30% of Schizophrenia patients. Reliable identification of TRS patients within an Electronic Health Record (EHR) system will improve [...]
Probing Gene-environment Interactions in Schizophrenia and Stress: Integrating human GWAS and mouse models | McElligott | $60,000
Probing Gene-environment Interactions in Schizophrenia and Stress: Integrating human GWAS and mouse models 2020 Award: $60,000 Schizophrenia is a heritable disorder that is impacted by environmental influences like stressful life experience. Studies have demonstrated thousands [...]
Dissection of Top-down Cortical Circuits Underlying Auditory Oddball Response, a Biomarker for Schizophrenia | Kato | $40,000
Dissection of Top-down Cortical Circuits Underlying Auditory Oddball Response, a Biomarker for Schizophrenia 2020 Award: $40,000 Hallucination, or “hearing voices” is one of the most prevalent symptoms of schizophrenia. In this project we will [...]
Randomized controlled trial of pyridoxine for tardive dyskinesia | Jarskog | $99,900
Randomized controlled trial of pyridoxine for tardive dyskinesia 2017 Award: $99,900 To date, the only effective medications to treat the symptoms associated with schizophrenia are the “antipsychotic” class of medications. Unfortunately, these medications have [...]