SCHIZOPHRENIA RESEARCH
$1,848,867 awarded to research since 1985
Schizophrenia is a serious mental illness that inhibits a person’s ability to think clearly, recognize reality, interact with others, and manage emotions. Symptoms can include hallucinations, delusions, hearing voices, flat emotional expression, and disorganized or obsessive thinking. While the disease isn’t common, it still affects 3.2 million Americans, and can have devastating consequences for a sufferer’s ability to keep a job or maintain interpersonal relationships. Despite its relative lack of prevalence, its severity and high mortality rate makes schizophrenia the Foundation’s most highly funded area of study.
Active Research
Investigation of D2 and 5-HT2A Genetic Variants on Antipsychotic Responsiveness | Dr. Ranran French | $57,705
Investigation of D2 and 5-HT2A Genetic Variants on Antipsychotic Responsiveness 2025 Award: $57,705 Many patients with schizophrenia endure months or even years of suboptimal treatment before finding an antipsychotic that works. This project aims [...]
Modeling Genetic Risk for Schizophrenia | Dr. Robert Mealer | $60,000
Modeling genetic risk for schizophrenia in human-derived neurons 2025 Award: $60,000 Over 75% of the risk for developing schizophrenia is determined by the genes one inherits. In this project, the Mealer and Heinzen Labs [...]
Development of Individual Differences in Adolescent Brain Structure and Risk | Cohen, Gilmore | $150,989
Development of Individual Differences in Adolescent Brain Structure and Risk 2024 Award: $150,989 Executive function is a critical ability that leads to better life outcomes, while low levels of executive function are a risk [...]
White Matter Connectome and Behavior Relationships in Early Childhood | Hong | $27,044
White Matter Connectome and Behavior Relationships in Early Childhood 2023 Award: $27,044 Despite increasing research on the association between brain structure and cognition/behavior in adults, their relationship in early childhood remains largely unknown. We [...]
Developing and Evaluating a Computable Phenotype for Treatment-Resistant Schizophrenia | Zeng | $41,302
Developing and Evaluating a Computable Phenotype for Treatment-Resistant Schizophrenia 2021 Award: $41,302 Treatment-Resistant Schizophrenia affects about 30% of Schizophrenia patients. Reliable identification of TRS patients within an Electronic Health Record (EHR) system will improve [...]