15 05, 2023

A Machine Learning Approach to Classify Medical Records by Psychiatric Diagnosis | Nash | $35,784

A Machine Learning Approach to Classify Medical Records by Psychiatric Diagnosis 2023 Award: $35,784 The widespread adoption of electronic health records (EHRs) has been accompanied by the enticing promise of using “big data” to improve patient care and clinical research. Many “big data” models rely on discrete data points, while in the field of mental health, our outcomes and diagnostic criteria are typically found in unstructured clinical narratives. In this study, we will train and evaluate machine learning classification models of psychiatric diagnoses using software capable of mining structured and unstructured data in the EHR, by incorporating unstructured clinical data using natural language processing. Need/Problem: The widespread adoption of electronic health records (EHRs) is accompanied by the enticing promise of using “big data” to improve patient care through large-scale research studies, population health and quality improvement initiatives, and improved [...]

16 04, 2019

Functional Development Abnormalities Associated with Genetic Risk of Bipolar during Infancy | Gao | $71,302

Functional Development Abnormalities Associated with Genetic Risk of Bipolar during Infancy 2013 Award: $71,302 Bipolar disorder (BD) is a common psychiatric illness affecting ~1% to 2% of the population, which is characterized by affective symptoms varying between depression and mania. However, there is a profound lack of knowledge regarding the brain’s functional disruption mechanism underlying this disorder, especially during early childhood which is increasingly recognized as a critical time for this neurodevelopmental disorder. The use of neuroimaging technology to study infants with a genetic risk of BD (biological mother diagnosed with BD) provides a wonderful opportunity to investigate the earliest functional disruption mechanisms related to this disorder, which is critical for the derivation of new early diagnosis and intervention strategies. Dr. Wei Gao, Assistant Professor of Radiology and Biomedical Imaging Research Center (BRIC) at the University of North Carolina [...]