Anxiety Disorders

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23 06, 2020

A Web-based Intervention to Improve Mental Health Outcomes Among Newly Diagnosed Parents with Cancer | Park | $39,997

A Web-based Intervention to Improve Mental Health Outcomes Among Newly Diagnosed Parents with Cancer 2020 Award: $39,997 Parental cancer threatens the mental health of the entire family. High-quality parental communication supports and facilitates psychological adjustment to illness for both parents and children, but many parents do not have timely access to these important mental health services. In this project we will develop and test a novel web-based psychosocial intervention designed to facilitate parental communication about cancer. If effective, this intervention could provide timely, cost-effective mental health support to address the communication concerns of distressed parents with cancer, thus improving mental health outcomes for their children as well. Need/Problem: Serious illness in a parent threatens the mental health of the entire family. The impact of parental cancer on the family can be reduced by facilitating parents’ communication about illness with [...]

10 06, 2020

A Translational Approach to Identify Biomarkers of COVID-19-related Social Stress in Healthcare Workers | Zannas & Rodriguez-Romaguera | $85,000

A Translational Approach to Identify Biomarkers of COVID-19-related Social Stress in Healthcare Workers 2020 Award: $85,000 Psychosocial stress is ubiquitous in modern societies and - especially when excessive or persistent - can lead to several psychiatric disorders, including major depressive, post-traumatic stress, and anxiety disorders. As we have all observed in the news recently, one of the most vulnerable populations in the COVID-19 pandemic is our healthcare providers. Our research will integrate human studies and preclinical mouse models of social stress to understand how persistent social stress affects this population. Need/Problem: Stress-related psychiatric disorders, including major depressive, post-traumatic stress, and anxiety disorders, are the most common mental illnesses in the United States. With the recent COVID-19 pandemic, both the Center for Disease Control (CDC) and the National Institute of Health (NIH) predict that the number of people suffering from [...]

29 08, 2019

Dissecting the Neural Circuits of Hyperarousal States in Psychiatry | Rodriguez-Romaguera | $200,000

Dissecting the Neural Circuits of Hyperarousal States in Psychiatry 2019 Award: $200,000 Anxiety is a complex state consisting of cognitive, emotional, and physiological components driven by a network across multiple brain regions. In this project, we plan on studying the neural circuits that regulate the hyperarousal state that often precedes the cognitive and emotional changes. Establishing the precise neural circuits involved in hyperarousal is critical to design novel therapeutic interventions for anxiety disorders. Need/Problem: Anxiety disorders are the most common mental illnesses in the United States, but we still poorly understand how specific neural circuits in the brain are affected during these disorders. Anxiety disorders are often characterized by an amplified arousal response to anxiogenic stimuli (hyperarousal). Grant Summary: Using pre-clinical mouse models we will use state-of-the-art microscopy techniques to visualize and record the activity of hundreds of individual [...]