Next Generation Non-Invasive Brain Stimulation: A Novel Solution Enabled by Mobile Technology and Big Data
We know that applying very weak electric currents to the scalp, a process called transcranial current stimulation (TCS), can boost specific rhythmic activity patterns in the brain that are the foundation of cognition and behavior. Dr. Frohlich and his team proposed a mobile brain stimulator that would connect to central database, enabling researchers to study the clinical effects of TCS from a nationwide set of data. This could lead to a major breakthrough on how to treat mentally ill patients using methods that are safe, noninvasive, and effective.
Flavio Frohlich, Ph.D.
Need/Problem: Psychiatry urgently needs new treatment paradigms that are effective, safe, and affordable. Non-invasive brain stimulation such as transcranial current stimulation has the potential to take such a role of a disruptive technology that will fundamental improve the landscape of treatment options for psychiatric disorders.
Grant Summary: Today, the field of transcranial current stimulation (TCS) is dominated by small, underpowered studies performed by individual, relatively isolated research groups. We argue that the solution to this problem is new device technology that allows the centralized execution and large-scale analysis of multiple TCS clinical studies.
Goals & Projected Outcomes: To implement and evaluate a networked and portable TCS device and server-side cloud-based infrastructure for remote control and collection of data on TCS and its clinical efficacy by means of centrally-managed clinical trials.
Grant Details: At completion of the proposed project, we will have developed a highly innovative technological solution that will transform how clinical trials with TCS will be performed. We plan to publish a report based on our user experience in Year 3 to disseminate our findings on the feasibility of our approach for the real-world use in clinical trials.